data:image/gif;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=

Join our fight to make the world a better place

Join our fight to make the world a better placeJoin our fight to make the world a better placeJoin our fight to make the world a better place

Together we can make a difference and change lives

Donate Now

215-904-6946

Join our fight to make the world a better place

Join our fight to make the world a better placeJoin our fight to make the world a better placeJoin our fight to make the world a better place

Together we can make a difference and change lives

Donate Now

215-904-6946

About Phelan-Mcdermid Syndrome

 Phelan-McDermid syndrome (PMS), also known as 22q13 deletion syndrome, is a rare genetic disorder that can affect people of all genders. It's caused by a mutation or deletion of the SHANK3 gene, or a deletion of part of chromosome 22. PMS can cause a wide range of symptoms that vary in severity, including:


  • Developmental delays: Delayed sitting up, rolling over, walking, or talking
  • Speech delays: Absent or severely delayed speech
  • Behavioral problems: Repetitive behaviors, anxiety, or nervousness
  • Motor skills deficits: Hypotonia (low muscle tone)
  • Autism spectrum disorder (ASD): PMS is one of the most common single gene forms of autism
  • Minor dysmorphic features: Long head shape, large or prominent ears, full brow, deep-set eyes, long eyelashes, full or puffy eyelids, droopy eyelids, flat midface, full or puffy cheeks, wide nasal bridge, bulbous nose, and pointed chin
  • Other features: Large fleshy hands, dysplastic toenails, decreased perspiration, difficulty falling asleep, numerous night awakenings, restless sleep, night-time incontinence, and tooth grinding

Who We Are - Divina-Rose Helping Hands Foundation

Our Vision

Our Approach

Our Approach

 Our vision is to help provide goods and services to better the lives of people with Phelan-Mcdermid and the families that provide for them. 

Our Approach

Our Approach

Our Approach

At Divina-Rose Helping Hands Foundation, our  approach is to helping the diagnosed live a full and meaningful life.

Our Impact

Our Approach

Our Impact

Having family diagnosed with this rare genetic syndrome, we are striving to help others meet their goals. as they prepare and maneuver for the  changing world ahead.

Images of Impact: A Visual Journey of Divina-Rose Helping Hands Foundation's Outreach

Support Divina-Rose Helping Hands Foundation

Your donation makes a difference in the lives of the Phelan-Mcdermid community.

Donate Now

Does someone you know or love with Pms need help?

Divina-rosehelpinghands@comcast.net

We would love to hear from you!

Divina-Rose Helping Hands Foundation

4618 thompson st Philadelphia PA 19137

215-904-6946

How can we help?

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Cancel

Stay in Touch

Sign up to hear from us about everything we are working on currently and future plans.

Copyright © 2024 Divina-Rose Helping Hands Foundation - All Rights Reserved.

This website uses cookies.

We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.

Accept